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TAKHZYRO (lanadelumab-flyo) is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in people 2 years of age and older. It is not known if TAKHZYRO is safe and effective in children under 2 years of age.

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TAKHZYRO (lanadelumab-flyo) is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in people 2 years of age and older. It is not known if TAKHZYRO is safe and effective in children under 2 years of age.

You’re here to support someone with HAE. We’re here to support you.

This page is full of TAKHZYRO resources—because we know that taking care of a loved one with hereditary angioedema (HAE) comes with questions and concerns. Learn what to expect once they start their treatment—and how to help them stay on track.

A real TAKHZYRO® patient, Kelly, with her partner and caregiver, Scott, by a campfire.


adults and adolescents Have been prescribed Takhzyro Since 2018*

*Based on third-party US specialty pharmacy data.

What to expect when
your loved one starts TAKHZYRO

Your loved one and their doctor likely chose to manage their HAE with TAKHZYRO for several reasons. One of those may have had to do with the results of the clinical studies. In those studies, people taking TAKHZYRO had fewer HAE attacks on average, and some even had periods of time with zero attacks.

If you’re caring for a child with HAE, you can find information about HAE in children. You can also explore our pediatric brochure for tips and support on helping your child stay on track with treatment.

Download Pediatric Brochure

Find more details on getting started with TAKHZYRO.


Help your loved one start off right

Your loved one's doctor prescribed TAKHZYRO to help them reduce the frequency of their HAE attacks.

Make sure your loved one remembers why they started taking TAKHZYRO.

Sticking to their HAE preventive treatment plan is the best way to help stay ahead of future attacks. Also, it’s important to make sure you or your loved one has an emergency plan in place in case of a life-threatening attack.

It’s possible your child may experience breakthrough attacks while taking TAKHZYRO. Some children may experience them more frequently in the first few months of treatment.

Your child’s on-demand medication should be readily available at all times in case of a breakthrough attack.

Encourage them to keep taking TAKHZYRO as prescribed and continue to reimagine their life with HAE.

TAKHZYRO is the #1 prescribed preventive treatment* in HAE and is approved for patients 2 years of age and older.

*Based on total patients on HAE preventive treatments according to US third-party industry healthcare data.

TAKHZYRO is an injection taken under the skin. No reconstitution is needed and it comes ready to use in a prefilled syringe.

Image of Dylan, real TAKHZYRO®  patient.
I'm lucky to have people who support me, and I'm not afraid to ask for their help. In a way, they're part of my HAE team. They give me the support I need to stay on track.
Dylan Real TAKHZYRO patient

Need some inspiration? See how Jack, a real TAKHZYRO patient, set his treatment goals.

Watch video

The importance of staying on track

As a caregiver, you play an important role in reminding your loved one to take TAKHZYRO exactly as their healthcare provider prescribed it. This means not skipping or missing doses. TAKHZYRO is a subcutaneous injection taken every 2 weeks. It’s eliminated as the body processes it, so it needs to be taken consistently.

A few ideas for remembering doses

Find ideas for helping you and your loved one remember their doses and other ways they can stay on track with their goals.

Find Tips

They’re here to remind you, “you can do this”

Watch other caregivers share perspectives on taking care of a loved one with HAE—and how important it is to realize that you’re not alone.

What advice do you have for other caregivers?

View Transcript

Educate yourself, be prepared, remember there's a community of support out there—hear more thoughts and advice from fellow caregivers.

BOBBI: For other caregivers dealing with HAE, I think the biggest thing you could do is just be supportive and try to understand even if you don't truly understand what that person is going through. But just be there, and love them through it.

JASON: My advice to a new caregiver is to ask a lot of questions, get a lot of answers, and don't be scared to ask questions. There's a lot of people out there that can help, have answers, that they have gone through in their life. It may help them out.

PAM: I would tell caregivers first of all, if you don't have HAE, is to find out about it, to-to know what's going on, and what things need to be done because sometimes those attacks can be an emergency or a life-threatening situation. So, you need to be prepared about what needs to happen for the person who is having the attack. And then I think it's to be sensitive to what's going on with them, to find out or look for clues as to when they might be having attacks coming on, and they may not even recognize it themselves.

JUAN: What I would like say to other caregivers is don't lose hope. There is support out there. There is help out there, and there's a community of people that have gone through the same exact situation that you are in, and there are people that you can talk to.

NARRATOR: TAKHZYRO® (lanadelumab) is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in people 2 years of age and older. It is not known if TAKHZYRO is safe and effective in children under 2 years of age.

NARRATOR: TAKHZYRO may cause serious side effects, including allergic reactions. Call your healthcare provider or get emergency help right away if you have any of the following symptoms: wheezing, difficulty breathing, chest tightness, fast heartbeat, faintness, rash, and/or hives. The most common side effects seen with TAKHZYRO were injection site reactions (pain, redness, and bruising), upper respiratory infection, headache, rash, dizziness, diarrhea, and muscle aches. These are not all the possible side effects of TAKHZYRO. For more information, ask your healthcare provider or pharmacist.

NARRATOR: You may report side effects to FDA at 1-800-FDA-1088. TAKHZYRO has not been studied in pregnant or breastfeeding women. Talk to your healthcare provider about the risk of taking TAKHZYRO if you are pregnant, plan to be pregnant, are breastfeeding, or plan to breastfeed. Talk to your healthcare provider about TAKHZYRO, the only preventive HAE treatment you take as a subcutaneous injection just once every two weeks.

Image of Juan, real TAKHZYRO®  caregiver.
The best thing about being a caregiver is being able to advocate for your loved one and being able to make sure they get the care they need.
Juan Partner and caregiver

Looking for more helpful info and tools? Check out our Patient Resources.

Find resources

Frequently Asked Questions

Is training available for caregivers who want to learn how to give TAKHZYRO to their loved ones?

Absolutely! Once somebody has been prescribed TAKHZYRO, they become eligible for a free product support program called OnePath®. This service gives those living with HAE and their caregivers the opportunity to receive at-home injection training via a trained nursing professional. Be sure to arrange for this as soon as possible to make sure you and your loved one are comfortable with the injection process and know what to do.

As a caregiver, how can I make sure I am also taking care of myself while helping my loved one through their TAKHZYRO treatment?

Caregiving is hard work, so it’s important to take care of yourself every chance you get. Remembering to accept help from others and seeking assistance when needed are two things that can help you have time for stress management. Eating nutritious foods and sleeping for enough time at regular intervals also go a long way in maintaining your physical health. Creating a calendar for treatment days can also assist in relieving the stress of missing a necessary injection.

What resources can help caregivers keep their loved ones on track with their treatment?

There are several resources caregivers might find helpful. The TAKHZYRO Text Reminder Program can help make sure you never miss a date by sending messages when it’s time for the next dosage. On top of that, the TAKHZYRO Journey Journal can help you easily keep track of dosing days, attacks, and your loved one’s management plan. OnePath® can also provide support by offering educational materials, financial assistance options, and regular check-ins with a Patient Support Manager (PSM).

What kind of information should caregivers prepare for future doctor appointments or hospital visits?

Caregivers have many things they need to pay attention to in the day-to-day lives of their loved ones living with HAE. These can include:

  • Any new health issues
  • How often they use on-demand medication
  • New or existing HAE triggers. These may include stress, exhaustion, hormonal fluctuation, or physical activity
  • The location, intensity, and duration of all attacks
  • What their attacks were like before preventive treatment and what they’re like now

Your loved one can use the Journey Journal to track these details. As a caregiver, you can help them update this journal and share it with their doctor. This can help everyone see how much progress they’ve made with their treatment goals.

OnePath® logo.

OnePath® is here to support you and your loved one while they're taking TAKHZYRO.

Discover OnePath
A body outline with dots on the three TAKHZYRO® injection sites (arm, abdomen, and leg).

Do you or your loved one need a refresher on injecting TAKHZYRO?

See the steps