TAKHZYRO is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in people 12 years of age and older. It is not known if TAKHZYRO is safe and effective in children under 12 years of age.

TAKHZYRO is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in people 12 years of age and older. It is not known if TAKHZYRO is safe and effective in children under 12 years of age.

What is Takhzyro?

TAKHZYRO is a prescription medicine that’s taken regularly to help prevent HAE attacks

A real TAKHZYRO® patient, Camila, and her husband, Jorge, boarding a trolley
Jorge
Camila

Hereditary angioedema (HAE) is a rare disorder that can cause sudden attacks of swelling anywhere in the body. If you have HAE, you try not to let attacks hold you back. But you also know how unpredictable they can be. What would fewer attacks mean to you?

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1 SUBCUTANEOUS
SELF-INJECTION
EVERY 2 WEEKS

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FEWER ATTACKS OR ZERO ATTACKS IN A STUDY

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PLASMA FREE

TAKHZYRO is made using cells in a lab--so it does not depend on human plasma donations.

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In a 26-week clinical trial of 125 people with HAE 12 years of age and older, TAKHZYRO significantly reduced the number of monthly attacks, compared with placebo. People taking TAKHZYRO also had fewer moderate or severe attacks and fewer attacks requiring acute treatment, compared with placebo. And according to a supportive analysis, there were people taking TAKHZYRO who had zero attacks during the entire trial.

The recommended dose is 300 mg every 2 weeks for people starting on TAKHZYRO.

If you have zero attacks for more than 6 months, your doctor may consider prescribing TAKHZYRO 300 mg once every 4 weeks.

See Sebastian's Reimagine Story

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SEBASTIAN: A bad month for me would be just constantly swollen. Something would be always swollen. A good month would be probably going a full week with maybe one attack. Yeah, that’d be a good month. Hi, I’m Sebastian, and this is my reimagine story. I grew up like most kids with HAE. Having odd swellings here and there. I remember going to school wearing slippers because my feet were too swollen for my shoes to fit.

SEBASTIAN: Doctors always dismissed my swellings as consequences of roughhousing. But my life changed the day I had a laryngeal, or throat, attack. I was studying for a finals exam when I felt my airway constricting. I quickly realized my throat was swelling. My mom picked me up at school and sped her way to the hospital. By the time we arrived, my throat was swollen shut, and I was intubated for two days. My condition went from being a nuisance to life-threatening in 3 hours. Thankfully, an HAE specialist happened to be visiting the hospital while I was there and made my diagnosis.

SEBASTIAN: As time went on, my HAE worsened. Seven to 10 attacks a month became the norm. Eventually, I started taking on-demand treatment, but I was still living my life around attacks. What was even more upsetting was that my children began to realize I was sick. I knew it was time to do more than just treating attacks reactively. I pride myself in being an involved patient, and given my background in science, I’ve always had an interest in learning how to prevent attacks.

SEBASTIAN: That’s what led me to ask my doctor about TAKHZYRO®, a once-every-two-week subcutaneous injection used to prevent HAE attacks in people 12 years of age and older. My doctor and I discussed the potential risks, such as serious side effects, including allergic reactions, as well as more common risks, including injection site reactions, upper respiratory infections, and headaches. After considering the benefits and potential risks, we moved forward with TAKHZYRO. Since starting, the frequency and severity of my attacks has lessened, and my on-demand treatment has gone unused for a while.

SEBASTIAN: I’ve even gone months without an attack. But these are my experiences, and not everyone will be the same. I have to be active and available for my 3 little ones. It means the world to me to be able to play catch or work in the garden with them. But my favorite way to spend time with my family is going to the beach. I hope my reimagine story will help others, especially my family members with HAE. I want them to know HAE may be tough, but so are you. If you are interested in learning more about reimagining your life with HAE, talk to your healthcare provider to see if TAKHZYRO is right for you.

NARRATOR: TAKHZYRO (lanadelumab) is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in people 12 years of age and older. It is not known if TAKHZYRO is safe and effective in children under 12 years of age. TAKHZYRO may cause serious side effects, including allergic reactions. Call your healthcare provider, or get emergency help right away if you have any of the following symptoms: wheezing, difficulty breathing, chest tightness, fast heartbeat, faintness, rash, and/or hives.

NARRATOR: The most common side effects seen with TAKHZYRO were injection site reactions (pain, redness, and bruising), upper respiratory infection, and headache. These are not all the possible side effects of TAKHZYRO. For more information, ask your healthcare provider or pharmacist. You may report side effects to the FDA at 1-800-FDA-1088. TAKHZYRO has not been studied in pregnant or breastfeeding women. Talk to your healthcare provider about the risk of taking TAKHZYRO if you are pregnant, plan to be pregnant, are breastfeeding, or plan to breastfeed.

NARRATOR: Talk to your healthcare provider about TAKHZYRO, the only preventive HAE treatment you take as a subcutaneous injection just once every two weeks.

I was living my life around attacks. What’s worse, my children began to notice I was sick. I knew it was time to do more than just treating attacks reactively… That’s what led me to ask my doctor about TAKHZYRO.
Sebastian Real TAKHZYRO patient
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Are you ready to reimagine your life with fewer HAE attacks?

You might be interested to know TAKHZYRO has been studied in more people with HAE than any other preventive treatment. Want all the details?

What could TAKHZYRO do for you?

If you’re ready to reimagine how often you have attacks and how often you take preventive treatment, it’s time to talk to your doctor about TAKHZYRO. This doctor discussion guide can help you start the conversation.

WHAT IS TAKHZYRO?

TAKHZYRO is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in people 12 years of age and older.

It is not known if TAKHZYRO is safe and effective in children under 12 years of age.

IMPORTANT SAFETY INFORMATION

TAKHZYRO may cause serious side effects, including allergic reactions. Call your healthcare provider or get emergency help right away if you have any of the following symptoms:

  • wheezing
  • difficulty breathing
  • chest tightness
  • fast heartbeat
  • faintness
  • rash
  • hives

The most common side effects seen with TAKHZYRO were injection site reactions (pain, redness, and bruising), upper respiratory infection, and headache.

These are not all the possible side effects of TAKHZYRO. For more information, ask your healthcare provider or pharmacist. You may report side effects to the FDA at 1-800-FDA-1088.

TAKHZYRO has not been studied in pregnant or breastfeeding women. Talk to your healthcare provider about the risk of taking TAKHZYRO if you are pregnant, plan to be pregnant, are breastfeeding, or plan to breastfeed.

Please see full Prescribing Information, including information for patients.